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Topic Question Set

Q 11 :

The α-Helix and β-pleated sheet structures of protein are associated with its:                [2025]

  • quaternary structure

     

  • primary structure

     

  • secondary structure

     

  • tertiary structure

     

(3)

The secondary structure of protein refers to the shape in which a long polypeptide chain can exist. They are found to exist in two different types of structures viz. α-helix and β-pleated sheet structure. These structures arise due to the regular folding of the backbone of the polypeptide chain due to hydrogen bonding between –CO– and –NH– groups of the peptide bond.

 

Q 12 :

Identify the essential amino acids from below:                         [2025]

(A) Valine
(B) Proline
(C) Lysine
(D) Threonine
(E) Tyrosine

Choose the correct answer from the options given below:

  • (A), (C) and (D) only

     

  • (C), (D) and (E) only

     

  • (B), (C) and (E) only

     

  • (A), (C) and (E) only

     

(1)

 

Q 13 :

Number of cyclic tripeptides formed with 2 amino acids A and B is:             [2023]

  • 2

     

  • 4

     

  • 3

     

  • 5

     

(2)

AAA, BBB, ABA, BAB are 4 possible cyclic structures.

Q 14 :

Following tetrapeptide can be represented as

(F, L, D, Y, I, Q, P are one letter codes for amino acids)             [2023]

  • PLDY

     

  • FLDY

     

  • FIQY

     

  • YQLF

     

(2)

Amino acid chain or peptide chain is often named starting from N-terminal ending towards C-Terminal. So FLDY is the best combination.

 

Q 15 :

A protein ‘X’ with molecular weight of 70,000 u, on hydrolysis gives amino acids. One of these amino acid is              [2023]

  •  

  •  

  •  

  •  

(2)

All proteins are polymers of α-amino acids.

 

Q 16 :

Match List I with List II.               [2023]

  List I   List II
  Natural Amino acid   One Letter Code
A. Arginine I. D
B. Aspartic acid II. N
C. Asparagine III. A
D. Alanine IV. R

Choose the correct answer from the options given below:

  • A-IV, B-I, C-III, D-II

     

  • A-III, B-I, C-II, D-IV

     

  • A-I, B-III, C-IV, D-II

     

  • A-IV, B-I, C-II, D-III

     

(4)

Q 17 :

Sulphur (S) containing amino acids from the following are:

a) isoleucine
b) cysteine
c) lysine
d) methionine
e) glutamic acid                                   [2023]

  • a, d

     

  • a, b, c

     

  • b, c, e

     

  • b, d

     

(4)

Cysteine and methionine contain S-atom.

 

Q 18 :

Match List I with List II.                   [2023]

  List I   List II
  Natural amino acid   One letter code
A. Glutamic acid I. Q
B. Glutamine II. W
C. Tyrosine III. E
D. Tryptophan IV. Y

Choose the correct answer from the options given below:

  • A-IV, B-III, C-I, D-II

     

  • A-III, B-IV, C-I, D-II

     

  • A-II, B-I, C-IV, D-III

     

  • A-III, B-I, C-IV, D-II

     

(4)

 

Q 19 :

The one that does not stabilize 2° and 3° structures of proteins is           [2023]

  • van der Waals forces

     

  • — S — S — linkage

     

  • H-bonding

     

  • — O — O — linkage

     

(4)

The main forces which stabilise the 2° and 3° structures of proteins are hydrogen bonding, disulphide linkages, van der Waals and electrostatic forces of attraction.

 

Q 20 :

The naturally occurring amino acid that contains only one basic functional group in its chemical structure is          [2023]

  • asparagine

     

  • lysine

     

  • histidine

     

  • arginine

     

(1)

Lysine, Arginine and Histidine are basic amino acids with one extra basic functional group, whereas Asparagine has additional-amide group, which is not classified as basic functional group.