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Solution


Q.

With the help of given pedigree, find out the probability for the birth of a child having no disease and being a carrier (has the disease mutation in one allele of the gene) in F3 generation.              [2025]
1 1/4  
2 1/2  
3 1/8  
4 Zero  

Ans.

(1)

As in the F1 generation the carrier female and non-affected (normal, not carrier) had affected male child that means the genetic disorder is sex-linked recessive.

The consanguineous mating between female (XcX) and male (XcY)

Out of 4 child only one is carrier i.e. 14.