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Solution


Q.

Which of the following immune responses is responsible for rejection of kidney graft              [2019]
1 Cell-mediated immune response  
2 Auto-immune response  
3 Humoral immune response  
4 Inflammatory immune response  

Ans.

(1)

Transplantation of tissue/organ often fails due to non-acceptance by the patient’s body. Therefore, tissue matching and blood group matching are essential before undertaking any graft/transplant. When the immune system recognises the protein in the transplanted tissue or organ as foreign, it initiates cellular immunity. As a result of this, there is a rejection of transplanted organs. To suppress the immune response during transplantation, histocompatibility antigen and immunosuppressants play an important role.