Q.

Transformation was discovered by                [2014]

1 Meselson and Stahl  
2 Hershey and Chase  
3 Griffith  
4 Watson and Crick  

Ans.

(3)

Transformation was first studied by S.F. Griffith in 1928 while studying Streptococcus pneumoniae. He found that R-type non-virulent bacteria pick up virulence from heat killed virulent S-type bacteria and transform into virulent forms. It was this experiment which indicated presence of a ‘transforming principle’ which was later found out to be DNA, by Avery et al.