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Solution


Q.

The association of histone H1 with a nucleosome indicates that              [2017]
1 DNA replication is occurring  
2 the DNA is condensed into a chromatin fibre  
3 the DNA double helix is exposed  
4 transcription is occurring  

Ans.

(2)

Histones help in packaging of DNA. In eukaryotes, DNA packaging is carried out with the help of positively charged basic proteins called histones. Histones are of five types – H1, H2A, H2B, H3 and H4. The association of H1 histone with nucleosome indicates that DNA remains in its condensed form. Nucleosome is the unit of compaction. H1 is attached over the linker DNA. The linker DNA, consisting of H1 histone, connects two adjacent nucleosomes. They together constitute chromatosome. It gives rise to a chromatin fibre after further condensation.