Q.

Select the correct option describing gonadotropin activity in a normal pregnant female.         [2014, 2012]

1 High level of FSH and LH stimulates the thickening of endometrium.  
2 High level of FSH and LH facilitates implantation of the embryo.  
3 High level of hCG stimulates the synthesis of estrogen and progesterone.  
4 High level of hCG stimulates the thickening of endometrium.  

Ans.

(3)

The trophoblastic cells secrete human chorionic gonadotropin hormone which has properties similar to those of luteinising hormone (LH) of the pituitary gland. It takes over the job of pituitary LH during pregnancy. The hCG maintains the corpus luteum and stimulates it to secrete progesterone. The latter maintains the endometrium of the uterus and causes it to grow throughout pregnancy. This also prevents menstruation. Progesterone also causes increased secretion of mucus in the cervix of the uterus that forms a protective plug during pregnancy.