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Solution


Q.

Select incorrect statement regarding chemical structure of insulin.              [2023]
1 Mature insulin molecule consists of three polypeptide chains - A, B and C.  
2 Insulin is synthesised as prohormone which contains extra stretch of C-peptide.  
3 C-peptide is not present in mature insulin molecule.  
4 Polypeptide chains A and B are linked by disulphide bridges.  

Ans.

(1)

Insulin consists of two short polypeptide chains—chain A and chain B—which are linked together by disulphide bonds. Insulin, in mammals, is synthesised as a prohormone which contains an extra stretch called the C-peptide. During maturation into insulin, this C-peptide is removed.