Q.

Pick out the correct statements.                                           [2016]
(1) Haemophilia is a sex-linked recessive disease.
(2) Down’s syndrome is due to aneuploidy.
(3) Phenylketonuria is an autosomal recessive gene disorder.
(4) Sickle cell anaemia is an X-linked recessive gene disorder.

1 (1), (3) and (4) are correct  
2 (1), (2) and (3) are correct  
3 (1) and (4) are correct  
4 (2) and (4) are correct  

Ans.

(2)

Sickle-cell anaemia is an autosomal recessive genetic disorder. It can be transmitted from parents to the offspring when both the partners are carriers of the gene (or heterozygous).