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Solution


Q.

In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self-cells, then it leads to:   [2016]
1 autoimmune disease  
2 active immunity  
3 allergic response  
4 graft rejection  

Ans.

(1)

Autoimmunity is a disorder of the body’s defence mechanisms in which an immune response is elicited against its own tissues, which are thereby damaged or destroyed. Autoimmunity may be caused due to genetic or environmental factors.