Q.

Identify the microorganism which is responsible for the production of an immunosuppressive molecule cyclosporin A.           [2022]

1 Trichoderma polysporum  
2 Clostridium butylicum  
3 Aspergillus niger  
4 Streptococcus cerevisiae  

Ans.

(1)

Cyclosporin A is used as immuno-suppressant. This drug is derived from a fungus, Trichoderma polysporum and is used to prevent rejection of kidney, heart and liver transplants. Cyclosporin inhibits the activity of helper T-cells that acts against foreign bodies.