Q.

How many times decarboxylation occurs during each TCA cycle              [2023]

1 Thrice  
2 Many  
3 Once  
4 Twice  

Ans.

(4)


In each TCA cycle two successive decarboxylation reactions occur, during the formation of α-ketoglutaric acid from oxalosuccinate and then succinyl CoA from α-ketoglutaric acid. Two CO2 molecules are released during these steps.