Q.

During deficiency of oxygen in tissues of human beings pyruvic acid is converted into lactic acid in :

1 Cytoplasm  
2 Chloroplast  
3 Mitochondria  
4 Golgi body  

Ans.

(1)

The pyruvate produced during glycolysis usually enters the Kreb’s cycle as acetyl coenzyme A in the mitochondrial matrix, where it provides a reservoir of chemical energy (ATP, NADH and FADH2). Pyruvic acid can be transformed to lactic acid as one of its potential fates in cellular respiration. Under stressful conditions, this often occurs in the cytoplasm of muscle tissue.