Doubling of the number of chromosomes can be achieved by disrupting mitotic cell division soon after [2023]
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Doubling of the number of chromosomes within a cell can be achieved by disrupting mitotic cell division soon after metaphase stage. After metaphase, each chromosome arranged at the metaphase plate splits and the two daughter chromatids begin their migration towards the two opposite poles to form two daughter cells. If this is prevented, chromosome number will get doubled.