Q.

Calcium is important in skeletal muscle contraction because it            [2018]

1 binds to troponin to remove the masking of active sites on actin for myosin  
2 activates the myosin ATPase by binding to it  
3 detaches the myosin head from the actin filament  
4 prevents the formation of bonds between the myosin cross bridges and the actin filament  

Ans.

(1)

Calcium ion plays an important role in skeletal muscle contraction. Muscle contraction is initiated by signal sent by the central nervous system. The neural signal further spreads through the muscle fibre and causes the release of calcium ions. Increase in calcium ion levels lead to the binding of calcium with a subunit of troponin on actin filaments and thereby remove the masking of active sites for myosin.