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Solution


Q.

Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur   [2017]
1 Chromosomes will be fragmented.  
2 Chromosomes will not segregate.  
3 Recombination of chromosome arms will occur.  
4 Chromosomes will not condense.  

Ans.

(2)

During anaphase in mitosis, sister chromatids segregate at opposite poles. Therefore, a defective APC will affect chromosome segregation.