Q.

A gene locus has two alleles A, a. If the frequency of dominant allele A is 0.4, then what will be the frequency of homozygous dominant, heterozygous and homozygous recessive individuals in the population                  [2019]

1 0.16 (AA); 0.36 (Aa); 0.48 (aa)  
2 0.36 (AA); 0.48 (Aa); 0.16 (aa)  
3 0.16 (AA); 0.24 (Aa); 0.36 (aa)  
4 0.16 (AA); 0.48 (Aa); 0.36 (aa)  

Ans.

(4)

Frequency of dominant allele (A) = 0.4

Applying Hardy-Weinberg equilibrium; p+q=1

q=1-0.4=0.6;  p2+q2+2pq=1

Frequency of homozygous dominant genotype

(p2  AA)=(0.4)2=0.16

Frequency of heterozygous genotype

(2pq  Aa)=2×0.4×0.6=0.48

Frequency of homozygous recessive genotype

(q2  aa)=(0.6)2=0.36