Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of [2023]
Lipase
Dinitrogenase
Succinic dehydrogenase
Amylase
(3)
In competitive inhibition, the inhibitor closely resembles the real substrate in its molecular structure and inhibits the activity of the enzyme. Due to its close structural similarity with the substrate, the inhibitor competes with substrate for the substrate binding site of enzymes. Consequently, the substrate cannot bind and as a result, the enzyme action declines.
Inhibition of succinic dehydrogenase by malonate is one example of competitive inhibition. Malonate closely resembles the substrate succinate in structure. Such competitive inhibitors are often used to inhibit the growth of pathogenic bacteria.
Given below are two statements:
Statement I: Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat.
Statement II: When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor.
In the light of the above statements, choose the correct answer from the options given below: [2023]
Statement I is true but Statement II is false.
Statement I is false but Statement II is true.
Both Statement I and Statement II are true.
Both Statement I and Statement II are false.
