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Topic Question Set

Q 1 :    

Match List I with List II.                                                                                       [2024]

  List I   List II
A. Citric acid cycle I. Cytoplasm
B. Glycolysis II. Mitochondrial matrix
C. Electron transport system III. Intermembrane space of mitochondria
D. Proton gradient IV. Inner mitochondrial membrane

 

Choose the correct answer from the options given below.

  • A-I, B-II, C-III, D-IV

     

  • A-II, B-I, C-IV, D-III

     

  • A-III, B-IV, C-I, D-II

     

  • A-IV, B-III, C-II, D-I

     

(2)

 

 

Q 2 :    

Identify the step in tricarboxylic acid cycle, which does not involve oxidation of substrate.                [2024]

  • Malic acid → Oxaloacetic acid

     

  • Succinic acid → Malic acid

     

  • Succinyl-CoA → Succinic acid

     

  • Isocitrate → α-ketoglutaric acid

     

(3)

 

Q 3 :    

How many times decarboxylation occurs during each TCA cycle?              [2023]

  • Thrice

     

  • Many

     

  • Once

     

  • Twice

     

(4)


In each TCA cycle two successive decarboxylation reactions occur, during the formation of α-ketoglutaric acid from oxalosuccinate and then succinyl CoA from α-ketoglutaric acid. Two CO2 molecules are released during these steps.

 

Q 4 :    

Match List I with List II:                                               [2023]

  List I   List II
A. Oxidative decarboxylation I. Citrate synthase
B. Glycolysis II. Pyruvate dehydrogenase
C. Oxidative phosphorylation III. Electron transport system
D. Tricarboxylic acid cycle IV. EMP pathway

 

Choose the correct answer from the options given below:

  • A-III, B-I, C-II, D-IV

     

  • A-II, B-IV, C-III, D-I

     

  • A-III, B-IV, C-II, D-I

     

  • A-II, B-IV, C-I, D-III

     

(2)

 

Q 5 :    

The number of substrate level phosphorylations in one turn of citric acid cycle is             [2020]

  • zero

     

  • one

     

  • two

     

  • three

     

(2)

In citric acid cycle, during the conversion of succinyl-CoA to succinic acid, a molecule of GTP is synthesized, which is called substrate level phosphorylation.

 

Q 6 :    

Where is respiratory electron transport system (ETS) located in plants?              [2019]

  • Mitochondrial matrix

     

  • Outer mitochondrial membrane

     

  • Inner mitochondrial membrane

     

  • Intermembrane space

     

(3)

 

Q 7 :    

Which of these statements is incorrect?                [2018]

  • Enzymes of TCA cycle are present in mitochondrial matrix.

     

  • Glycolysis occurs in cytosol.

     

  • Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms.

     

  • Oxidative phosphorylation takes place in outer mitochondrial membrane.

     

(4)

Oxidative phosphorylation is the synthesis of energy-rich ATP molecules with the help of energy liberated during oxidation of reduced coenzymes (NADH, FADH2) produced in respiration. The enzyme required for this synthesis is ATP synthase. It is located in F1 or head piece of F0-F1 or elementary particles present on the inner mitochondrial membrane.

 

Q 8 :    

Which statement is wrong for Krebs’ cycle?                    [2017]

  • There is one point in the cycle where FAD+ is reduced to FADH2.

     

  • During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised.

     

  • The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.

     

  • There are three points in the cycle where NAD+ is reduced to NADH + H+.

     

(3)

Krebs’ cycle starts with condensation of acetyl group (acetyl CoA) with oxaloacetate to form a tricarboxylic, 6-carbon compound called citric acid.

 

Q 9 :    

Oxidative phosphorylation is                  [2016]

  • formation of ATP by transfer of phosphate group from a substrate to ADP

     

  • oxidation of phosphate group in ATP

     

  • addition of phosphate group to ATP

     

  • formation of ATP by energy released from electrons removed during substrate oxidation.

     

(4)

Oxidative phosphorylation is the synthesis of energy-rich ATP molecules with the help of energy liberated during oxidation of reduced co-enzymes (NADH, FADH2) produced in respiration.

The enzyme required for this synthesis is called ATP synthase. It is located in F1 or head piece of F0–F1 or elementary particles present in the inner mitochondrial membrane. F1 particle is capable of ATP synthesis.

ATP synthase becomes active in ATP formation only when there is a proton gradient having higher concentration of H+ or protons on the F0 side as compared to F1 side. This higher concentration creates an electric potential across the mitochondrial membrane. The proton gradient and membrane electric potential together form proton motive force (PMF). The flow of protons through the F0 channel induces F1 particle to function as ATP synthase. The energy of the proton gradient is used in attaching a phosphate radical to ADP by high-energy bond. This produces ATP.

 

Q 10 :    

Cytochromes are found in               [2015]

  • cristae of mitochondria

     

  • lysosomes

     

  • matrix of mitochondria

     

  • outer wall of mitochondria.

     

(1)

Cytochrome is a group of proteins, each with an iron-containing haeme group. They are a part of the electron transport chain in mitochondria (present in cristae) and chloroplasts (in thylakoids).