Q 1 :    

Match List-I with List-II:                                 [2024]

  List - I   List - II
A. Common cold (I) Plasmodium
B. Haemozoin (II) Typhoid
C. Widal test (III) Rhinoviruses
D. Allergy (IV) Dust mites

 

Choose the correct answer from the options given below:

  • A-II, B-IV, C-III, D-I

     

  • A-I, B-III, C-II, D-IV

     

  • A-III, B-I, C-II, D-IV

     

  • A-IV, B-II, C-III, D-I

     

(3)

 



Q 2 :    

Given below are two statements:                                                                              [2024]

Statement I: Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are produced.
Statement II: Both bone marrow and thymus provide microenvironments for the development and maturation of T-lymphocytes.

In the light of the above statements, choose the most appropriate answer:

  • Both Statement I and Statement II are correct

     

  • Both Statement I and Statement II are incorrect

     

  • Statement I is correct but Statement II is incorrect

     

  • Statement I is incorrect but Statement II is correct

     

(1)

Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are produced. Both bone marrow and thymus provide micro-environments for the development and maturation of T-lymphocytes. After maturation the lymphocytes migrate to secondary lymphoid organs like spleen, lymph nodes, tonsils, Peyer’s patches of small intestine and appendix.

 



Q 3 :    

Match List I with List II                          [2023]

  List I   List II
(A) Cytokine barriers (I) Mucus coating of respiratory tract
(B) Cellular barriers (II) Interferons
(C) Physiological barriers (III) Neutrophils and macrophages
(D) Physical barriers (IV) Tears and saliva

 

Choose the correct answer from the options given below:

  • A-(II), B-(III), C-(IV), D-(I)

     

  • A-(III), B-(I), C-(IV), D-(II)

     

  • A-(III), B-(I), C-(II), D-(IV)

     

  • A-(II), B-(III), C-(I), D-(IV)

     

(1)

 



Q 4 :    

Given below are two statements:                                                              [2022]

Statement I: Autoimmune disorder is a condition where body defense mechanism recognizes its own cells as foreign bodies.
Statement II: Rheumatoid arthritis is a condition where body does not attack self cells.

In the light of the above statements, choose the most appropriate answer from the options given below:

  • Both Statement I and Statement II are correct

     

  • Both Statement I and Statement II are incorrect

     

  • Statement I is correct but Statement II is incorrect

     

  • Statement I is incorrect but Statement II is correct

     

(3)

Rheumatoid arthritis (RA) is a result of auto-immune reaction. In RA, immune system mistakenly attacks healthy self cells in our body, causing inflammation, painful swelling in the affected parts of the body.

 



Q 5 :    

Select the incorrect statement with respect to acquired immunity.                        [2022]

  • Primary response is produced when our body encounters a pathogen for the first time.

     

  • Anamnestic response is elicited on subsequent encounters with the same pathogen.

     

  • Anamnestic response is due to memory of first encounter.

     

  • Acquired immunity is non-specific type of defense present at the time of birth.

     

(4)

Acquired immunity is specific to pathogen. Innate immunity is non-specific type of defence present at the time of birth.

 



Q 6 :    

Identify the wrong statement with reference to immunity.                  [2020]

  • When exposed to antigen (living or dead) antibodies are produced in the host’s body. It is called “Active immunity”.

     

  • When ready-made antibodies are directly given, it is called “Passive immunity”.

     

  • Active immunity is quick and gives full response.

     

  • Fetus receives some antibodies from mother, it is an example for passive immunity.

     

(3)

Active immunity is slow and takes time to give its full effective response.

 



Q 7 :    

Which of the following immune responses is responsible for rejection of kidney graft?              [2019]

  • Cell-mediated immune response

     

  • Auto-immune response

     

  • Humoral immune response

     

  • Inflammatory immune response

     

(1)

Transplantation of tissue/organ often fails due to non-acceptance by the patient’s body. Therefore, tissue matching and blood group matching are essential before undertaking any graft/transplant. When the immune system recognises the protein in the transplanted tissue or organ as foreign, it initiates cellular immunity. As a result of this, there is a rejection of transplanted organs. To suppress the immune response during transplantation, histocompatibility antigen and immunosuppressants play an important role.

 



Q 8 :    

Colostrum, the yellowish fluid, secreted by mother during the initial days of lactation is very essential to impart immunity to the newborn infants because it contains:   [2019]

  • immunoglobulin A

     

  • natural killer cells

     

  • monocytes

     

  • macrophages

     

(1)

Colostrum (Mother's first milk) rich in immunoglobulin A (IgA) antibodies are passed to newborn through the breast feed and provides natural passive immunity.

 



Q 9 :    

Which of the following is not an autoimmune disease?                [2018]

  • Psoriasis

     

  • Rheumatoid arthritis

     

  • Alzheimer’s disease

     

  • Vitiligo

     

(3)

Autoimmune diseases are certain unrelated disorders caused by inflammation and destruction of tissues by the body's own immune response. These disorders include acquired hemolytic anaemia, pernicious anaemia, rheumatoid arthritis, myasthenia gravis, psoriasis, vitiligo, etc. Alzheimer’s disease is a chronic neurodegenerative irreversible, progressive brain disorder that slowly destroys memory and thinking skills.

 



Q 10 :    

Transplantation of tissues/organs fails often due to non-acceptance by the patient’s body. Which type of immune response is responsible for such rejections?     [2017]

  • Cell-mediated immune response

     

  • Hormonal immune response

     

  • Physiological immune response

     

  • Autoimmune response

     

(1)